Single-organ bioregulator peptides

Very short peptides from one Russian research group, each made to match one organ. 13 peptides, each with what researchers tested, its proof grade and its dose range.

Bioregulators are very short peptides, only 2 to 4 building blocks long. Nearly all of the work on them comes from one Russian research group (Khavinson and colleagues). Each one was made to match one organ, and most of the testing is in rats, old animals and cells in a dish.

"Studied for" means what researchers tested. It does not mean it works, or that it is safe or right for anyone. Check the proof grade: many of these were only tested in animals.

BronchogenAEDL, Ala-Glu-Asp-LeuAnimal studies onlySingle-organ bioregulatorsImmune system and inflammationThe lungs. In rats with COPD-like lung damage it reversed airway damage and lowered lung inflammation. No human trials.Common use: 10 mg per doseCardiogenAEDR, Ala-Glu-Asp-ArgAnimal studies onlySingle-organ bioregulatorsHeart, blood vessels and energyThe heart. Grew heart tissue in a dish and slowed tumors in old rats. No human trials.Common use: 1 mg to 10 mg per doseCartalaxAED, Ala-Glu-Asp, T-31Animal studies onlySingle-organ bioregulatorsHealing and recoveryCartilage and bone. Slowed bone loss in rats and helped old rat kidneys. No human trials.Common use: 700 mcg to 10 mg per doseChonlutenEDG, Glu-Asp-Gly, T-34Animal studies onlySingle-organ bioregulatorsImmune system and inflammationThe stomach and airways. Lowered inflammation signals in cells and helped stomach ulcer models. No human trials.Common use: 10 mg per doseCortagenAEDP, Ala-Glu-Asp-ProAnimal studies onlySingle-organ bioregulatorsBrain, mood and sleepThe brain and nerves. Sped up nerve regrowth in rats and helped brain recovery. No human trials.Common use: 10 mg per doseLivagenKEDA, Lys-Glu-Asp-AlaAnimal studies onlySingle-organ bioregulatorsAging and longevityThe liver and gut. In old rats it moved gut and liver cell activity toward young levels. No human trials.Common use: 1 mg to 5 mg per doseOvagenEDL, Glu-Asp-Leu, T-35Animal studies onlySingle-organ bioregulatorsThe liver and kidneys. Protected rat kidneys from damage. No human trials.Common use: 10 mg per dosePancragenKEDW, Lys-Glu-Asp-Trp-NH2, pancrageneAnimal studies onlySingle-organ bioregulatorsWeight and blood sugarThe pancreas and blood sugar. Lowered blood sugar in older people with diabetes and in monkeys.Common use: 10 mg per dosePinealonEDR, Glu-Asp-ArgAnimal studies onlySingle-organ bioregulatorsBrain, mood and sleepThe brain. Small Russian human studies on mood and biological age markers.Common use: 200 mcg to 5 mg per doseProstamaxKEDP, Lys-Glu-Asp-ProAnimal studies onlySingle-organ bioregulatorsThe prostate. Grew prostate tissue in a dish. No human trials.Common use: 10 mg per doseThymagenThymogen, Glu-Trp, EW dipeptide, oglufanide, IM862Human trialsSingle-organ bioregulatorsImmune system and inflammationThe thymus and immune system. Human trials in hepatitis C and cancer (as oglufanide) gave mixed results.Common use: 10 mcg to 10 mg per doseVesugenKED, Lys-Glu-Asp, vezugen, T-38Animal studies onlySingle-organ bioregulatorsHeart, blood vessels and energyBlood vessels. Small Russian human studies on biological age markers and mood.Common use: 10 mcg to 10 mg per doseVilonKE, Lys-GluAnimal studies onlySingle-organ bioregulatorsAging and longevityImmune system and inflammationThe immune system and aging. Longer life in mice, and added to diabetes care in Russian human studies.Common use: 100 mcg to 10 mg per dose

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