Peptides studied for aging and longevity

Lifespan, old cells, biological age and tumors in aging animals. 8 peptides, each with what researchers tested, its proof grade and its dose range.

"Studied for" means what researchers tested. It does not mean it works, or that it is safe or right for anyone. Check the proof grade: many of these were only tested in animals.

EpithalonEpitalon, AEDGAnimal studies onlyAging and longevityAging and tumors. In mice and rats it lowered tumor rates. From the same Russian group as the bioregulators.Common use: 2 mg to 15 mg per doseFOXO4-DRIFOXO4 D-Retro-Inverso, FOXO4-DRI peptideAnimal studies onlyAging and longevityClearing old, worn-out cells. In old mice, fitness, fur and kidney function came back.Common use: 250 mcg to 3 mg per doseHumaninHN, S14G-humanin, HNGAnimal studies onlyAging and longevityBrain, mood and sleepHeart, blood vessels and energyProtecting cells under stress. Rat studies on the heart after a heart attack and on brain cells.Common use: 1 mg to 3 mg per doseMOTS-cAnimal studies onlyAging and longevityWeight and blood sugarMetabolism and exercise capacity. In mice it prevented weight gain on a fatty diet and improved running in old mice.Common use: 5 mg per doseNAD+Nicotinamide adenine dinucleotideSmall human studiesAging and longevityHeart, blood vessels and energyCell energy and aging. Small human studies on how it moves through the body. Not a peptide.Common use: 20 mg to 100 mg per doseLivagenKEDA, Lys-Glu-Asp-AlaAnimal studies onlySingle-organ bioregulatorsAging and longevityThe liver and gut. In old rats it moved gut and liver cell activity toward young levels. No human trials.Common use: 1 mg to 5 mg per doseSS-31ElamipretideHuman trialsHeart, blood vessels and energyAging and longevityMitochondria (the cell's energy makers). Human trials in heart failure and mitochondrial muscle disease.Common use: 5 mg to 40 mg per doseVilonKE, Lys-GluAnimal studies onlySingle-organ bioregulatorsAging and longevityImmune system and inflammationThe immune system and aging. Longer life in mice, and added to diabetes care in Russian human studies.Common use: 100 mcg to 10 mg per dose

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